Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 19/20 | 0.68 |
| ▸ | NPY1R | P25929 | 12/20 | 0.68 |
| ▸ | NPY5R | Q15761 | 10/20 | 0.68 |
| ▸ | NPY2R | P49146 | 8/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30656922 | 1.00 | NPY4R (0.68) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL30656927 | 0.88 | NPY4R (0.51) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL29376517 | 0.88 | NPY4R (0.64) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL16508584 | 0.88 | NPY4R (0.66) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL31388270 | 0.88 | NPY4R (0.64) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL14520586 | 0.88 | NPY4R (0.60) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL13367326 | 0.88 | NPY4R (0.60) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL30656916 | 0.87 | MMP1 (0.48) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL16508586 | 0.87 | NPY4R (0.64) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL16508441 | 0.87 | NPY4R (0.64) | NPY4RNPY1RNPY5RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230357320-A1 | HELICAL STAPLED PEPTIDES AND USES THEREOF | PARABILIS MEDICINES, INC. | 2023-11-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230357320-A1 | HELICAL STAPLED PEPTIDES AND USES THEREOF | ESRRB, ESR1, ESRRA | NPY4R 59/4885NPY1R 18/4885NPY5R 78/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.