Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP3 | O14638 | 2/20 | 0.41 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20849808 | 0.82 | MGAM (0.32) | — | |
| SCHEMBL21170650 | 0.79 | PDE4A (0.38) | MEN1ALDH1A1KMT2A | |
| SCHEMBL21307499 | 0.75 | CCNB2 (0.35) | — | |
| SCHEMBL25802928 | 0.73 | ENPP3 (0.32) | ENPP3ENPP1 | |
| SCHEMBL18380996 | 0.73 | ENPP3 (0.32) | ENPP3ENPP1 | |
| SCHEMBL24200698 | 0.73 | ALDH1A1 (0.36) | KDM4EALDH1A1TDP1 | |
| SCHEMBL1150451 | 0.70 | ENPP3 (0.46) | ENPP3ENPP1KDM4EMEN1ALDH1A1 | |
| SCHEMBL24491130 | 0.69 | MAP3K8 (0.31) | — | |
| SCHEMBL21470789 | 0.69 | MGAM (0.31) | — | |
| SCHEMBL19730198 | 0.68 | FGFR1 (0.49) | ENPP3ENPP1MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023076849-A1 | INHIBITORS OF EPIDERMAL GROWTH FACTOR RECEPTOR | ORIC PHARMACEUTICALS, INC. (US) | 2023-05-04 | — | — | WO | disclosed |
| WO-2007067537-A1 | PYRROLOPYRIDINE KINASE INHIBITING COMPOUNDS | OSI PHARMACEUTICALS, INC. (US) | 2007-06-14 | — | — | WO | disclosed |