Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TET3 | O43151 | 4/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.72 |
| ▸ | FBXL19 | Q6PCT2 | 4/20 | 0.72 |
| ▸ | TET1 | Q8NFU7 | 4/20 | 0.72 |
| ▸ | KDM2B | Q8NHM5 | 4/20 | 0.72 |
| ▸ | CXXC4 | Q9H2H0 | 4/20 | 0.72 |
| ▸ | KDM2A | Q9Y2K7 | 4/20 | 0.72 |
| ▸ | CXXC5 | Q7LFL8 | 3/20 | 0.72 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2526026 | 0.83 | TET3 (0.64) | TET3KMT2AFBXL19TET1KDM2B | |
| SCHEMBL14520963 | 0.77 | OPRD1 (0.48) | TET3KMT2AFBXL19TET1KDM2B | |
| SCHEMBL12216179 | 0.76 | KMT2A (0.54) | TET3KMT2AFBXL19TET1KDM2B | |
| SCHEMBL2529201 | 0.75 | KMT2A (0.57) | TET3KMT2AFBXL19TET1KDM2B | |
| SCHEMBL31147394 | 0.75 | KMT2A (0.59) | TET3KMT2AFBXL19TET1KDM2B | |
| SCHEMBL2526312 | 0.75 | OPRM1 (0.59) | TET3KMT2AFBXL19TET1KDM2B | |
| SCHEMBL2527305 | 0.74 | CYP2C19 (0.55) | TET3KMT2AFBXL19TET1KDM2B | |
| Hydrochloric Acid SCHEMBL2529676 | 0.74 | OPRM1 (0.58) | TET3KMT2AFBXL19TET1KDM2B | |
| SCHEMBL14520964 | 0.73 | KMT2A (0.49) | TET3KMT2AFBXL19TET1KDM2B | |
| SCHEMBL27645407 | 0.73 | KMT2A (0.55) | TET3KMT2AFBXL19TET1KDM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070088036-A1 | Piperidine derivatives and methods of use | CHEMOCENTRYX, INC. (US) | 2007-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070088036-A1 | Piperidine derivatives and methods of use | CCR1, CCR3, CCR4 | TET3 4570/4885KMT2A 4268/4885FBXL19 3505/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.