Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | IDH1 | O75874 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8635094 | 0.72 | ALDH1A1 (0.32) | ROCK1ALDH1A1 | |
| SCHEMBL16361099 | 0.72 | SMN1; SMN2 (0.33) | ROCK1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL27500452 | 0.68 | ALDH1A1 (0.41) | PGRALDH1A1POLBAPOBEC3GTAAR1 | |
| SCHEMBL21882498 | 0.67 | MAOB (0.43) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL22243889 | 0.67 | NR1I3 (0.38) | PDE4BIDH1MAPTMEN1KMT2A | |
| SCHEMBL23969743 | 0.67 | IDH1 (0.31) | ALDH1A1IDH1MAPT | |
| SCHEMBL10145891 | 0.65 | HTR2C (0.37) | ROCK1HTR2C | |
| SCHEMBL23969704 | 0.64 | ESR2 (0.34) | ESR2 | |
| SCHEMBL15037756 | 0.64 | — | — | |
| SCHEMBL21091939 | 0.64 | PGR (0.38) | PGRALDH1A1POLBAPOBEC3GHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007050587-A2 | THERAPEUTIC COMPOSITIONS AND METHODS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2007-05-03 | — | — | WO | disclosed |