Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 12/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.41 |
| ▸ | LGMN | Q99538 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14527020 | 0.83 | NOTUM (0.53) | NOTUMALDH1A1KEAP1MAOAMAOB | |
| SCHEMBL14527021 | 0.82 | NOTUM (0.42) | NOTUMALDH1A1ALOX15MAPK10HSD17B10 | |
| SCHEMBL27621176 | 0.80 | NOTUM (0.50) | NOTUMALDH1A1KEAP1MAOAMAOB | |
| SCHEMBL5623484 | 0.74 | NOTUM (0.50) | NOTUMALDH1A1ALOX15MAPK10HSD17B10 | |
| SCHEMBL5622918 | 0.74 | NOTUM (0.52) | NOTUM | |
| SCHEMBL30538076 | 0.74 | NOTUM (0.63) | NOTUMKEAP1KCNH2 | |
| SCHEMBL24169257 | 0.72 | MAOA (0.81) | MAOAMAOBKCNH2F10 | |
| SCHEMBL5741706 | 0.72 | MAOA (0.81) | MAOAMAOBKCNH2F10 | |
| SCHEMBL28358734 | 0.71 | LGMN (0.51) | ALDH1A1ALOX15MAPK10HSD17B10MAOA | |
| SCHEMBL21792324 | 0.70 | NOTUM (1.00) | NOTUMKEAP1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7202254-B2 | Antibacterial compounds: process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S LABORATORIES LIMITED (IN) | 2007-04-10 | — | — | US | disclosed |
| US-7202254-B2 | Antibacterial compounds: process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S LABORATORIES LIMITED (IN) | 2007-04-10 | — | — | US | disclosed |