Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGMN | Q99538 | 2/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 4/20 | 0.44 |
| ▸ | HTR3B | O95264 | 4/20 | 0.44 |
| ▸ | HTR3A | P46098 | 4/20 | 0.44 |
| ▸ | HTR3D | Q70Z44 | 4/20 | 0.44 |
| ▸ | HTR3C | Q8WXA8 | 4/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.44 |
| ▸ | HTR5A | P47898 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | HTR7 | P34969 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8257644 | 0.82 | LGMN (0.50) | LGMNADRB1ALDH1A1ALOX15HSD17B10 | |
| SCHEMBL30221871 | 0.81 | ALDH1A1 (0.52) | ADRB1ALDH1A1HSD17B10HTR3EHTR3B | |
| SCHEMBL20521422 | 0.81 | ALDH1A1 (0.52) | ADRB1ALDH1A1HSD17B10HTR3EHTR3B | |
| SCHEMBL20521796 | 0.79 | ADRB1 (0.43) | ADRB1ALDH1A1HTR3EHTR3BHTR3A | |
| SCHEMBL478208 | 0.77 | ADRB1 (0.57) | ADRB1ALDH1A1HTR3EHTR3BHTR3A | |
| SCHEMBL233938 | 0.75 | KDR (0.53) | ALDH1A1HTR3AMAPTHTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL8318106 | 0.75 | ADRB1 (0.55) | ADRB1ALDH1A1HTR3EHTR3BHTR3A | |
| Hydrochloric Acid SCHEMBL28512966 | 0.75 | ADRB1 (0.55) | ADRB1ALDH1A1HTR3EHTR3BHTR3A | |
| Hydrochloric Acid SCHEMBL30892475 | 0.75 | ADRB1 (0.55) | ADRB1ALDH1A1HTR3EHTR3BHTR3A | |
| SCHEMBL29557426 | 0.75 | KDR (0.53) | ALDH1A1HTR3AMAPTHTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115991679-A | 2-oxothiazole derivatives as A2A inhibitors and compounds for the treatment of cancer | 伊忒欧斯比利时股份公司 | 2023-04-21 | — | — | CN | disclosed |
| CN-115873022-A | 2-oxothiazole derivatives as A2A inhibitors and compounds for the treatment of cancer | 伊忒欧斯比利时股份公司 | 2023-03-31 | — | — | CN | disclosed |
| CN-110678472-B | 2-oxothiazole derivatives as A2A inhibitors and compounds for the treatment of cancer | 伊忒欧斯比利时股份公司 | 2023-01-24 | — | — | CN | disclosed |
| CN-110678472-A | 2-oxothiazole derivatives as A2A inhibitors and compounds for the treatment of cancer | 伊忒欧斯治疗公司 | 2020-01-10 | — | — | CN | disclosed |