Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDX3X | O00571 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 8/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | PIKFYVE | Q9Y2I7 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8238479 | 0.90 | MAPT (0.61) | DDX3XMAPTKMT2AMEN1NPSR1 | |
| SCHEMBL11913671 | 0.85 | DDX3X (0.82) | DDX3XTDP1MAPTKMT2AMEN1 | |
| SCHEMBL22737346 | 0.84 | DDX3X (0.59) | DDX3XTDP1MAPTKMT2AMEN1 | |
| SCHEMBL8239323 | 0.79 | MAPT (0.51) | DDX3XMAPTKMT2AMEN1NPSR1 | |
| SCHEMBL22892510 | 0.75 | MAPT (0.59) | DDX3XTDP1MAPTKMT2AMEN1 | |
| SCHEMBL8241042 | 0.73 | TDP1 (0.84) | TDP1MAPTKMT2AMEN1NPSR1 | |
| SCHEMBL22737561 | 0.73 | GBA1 (0.49) | DDX3XTDP1MAPTKMT2AMEN1 | |
| SCHEMBL22737390 | 0.72 | GBA1 (0.47) | TDP1MAPTKMT2AMEN1NPSR1 | |
| SCHEMBL8238853 | 0.72 | DDX3X (0.61) | DDX3XTDP1MAPTKMT2AMEN1 | |
| SCHEMBL29345080 | 0.71 | TDP1 (0.76) | TDP1MAPTKMT2AMEN1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1790345-A1 | Triazin beta-secretase inhibitors | Esbatech AG (CH) | 2007-05-30 | — | — | EP | disclosed |