SCHEMBL14529092

SCHEMBL14529092

Cc1cccc(S(=O)(=O)/N=C/N(C)C)c1N

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.49
GAA P10253 1/20 0.49
CD44 P16070 1/20 0.36
BCAT1 P54687 1/20 0.33
F2 P00734 2/20 0.33
PRSS1 P07477 2/20 0.33
PRSS2 P07478 2/20 0.33
PRSS3 P35030 2/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
HTR2A P28223 1/20 0.32
HTR2C P28335 1/20 0.32
KMT2A Q03164 2/20 0.31
CA2 P00918 1/20 0.31
SUMO2 P61956 1/20 0.31
SUMO1 P63165 1/20 0.31
SENP7 Q9BQF6 1/20 0.31
SENP3 Q9H4L4 1/20 0.31
SENP2 Q9HC62 1/20 0.31
SENP1 Q9P0U3 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5011626 0.78 LMNA (0.45) LMNAGAABCAT1KDM4EALDH1A1
SCHEMBL5011622 0.78 LMNA (0.45) LMNAGAABCAT1KDM4EALDH1A1
SCHEMBL29716820 0.77 GAA (0.44) LMNAGAABCAT1F2PRSS1
SCHEMBL24686355 0.75 GAA (0.49) LMNAGAAKDM4EALDH1A1KMT2A
SCHEMBL8096686 0.72 LMNA (0.49) LMNAGAABCAT1KDM4EALDH1A1
SCHEMBL489291 0.72 LMNA (0.49) LMNAGAABCAT1ALDH1A1KMT2A
SCHEMBL10530946 0.72 LMNA (0.49) LMNAGAABCAT1ALDH1A1KMT2A
SCHEMBL29816630 0.72 LMNA (0.49) LMNAGAABCAT1ALDH1A1KMT2A
SCHEMBL11744143 0.72 CD44 (0.50) LMNAGAACD44KDM4EALDH1A1
SCHEMBL17013385 0.71 GAA (0.60) LMNAGAAF2KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007060220-A2 CYANOBENZENE COMPOUNDS FOR COMBATING ANIMAL PESTS BASF SE (DE) 2007-05-31 WO disclosed