Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.37 |
| ▸ | CASP1 | P29466 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19551919 | 0.83 | LMNA (0.44) | GAALMNAL3MBTL1ALDH1A1CYP3A4 | |
| SCHEMBL29718844 | 0.83 | LMNA (0.44) | GAALMNAL3MBTL1ALDH1A1CYP3A4 | |
| SCHEMBL19551921 | 0.83 | LMNA (0.44) | GAALMNAL3MBTL1ALDH1A1CYP3A4 | |
| SCHEMBL24686020 | 0.80 | GAA (0.41) | GAALMNAL3MBTL1ALDH1A1CYP3A4 | |
| SCHEMBL16639428 | 0.78 | LMNA (0.45) | GAALMNAL3MBTL1ALDH1A1CYP3A4 | |
| SCHEMBL27715369 | 0.78 | LMNA (0.42) | GAALMNAL3MBTL1ALDH1A1CASP1 | |
| SCHEMBL14336403 | 0.78 | GAA (0.42) | GAALMNAL3MBTL1ALDH1A1MAPT | |
| SCHEMBL29451752 | 0.76 | ALDH1A1 (0.56) | LMNAL3MBTL1ALDH1A1CASP1CYP3A4 | |
| SCHEMBL7537342 | 0.76 | ALDH1A1 (0.56) | LMNAL3MBTL1ALDH1A1CASP1CYP3A4 | |
| SCHEMBL14529092 | 0.75 | LMNA (0.49) | GAALMNAALDH1A1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022161416-A1 | AROMATIC COMPOUND, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 武汉朗来科技发展有限公司 | 2022-08-04 | — | — | WO | disclosed |