Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.47 |
| ▸ | NEU3 | Q9UQ49 | 2/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 12/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 12/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 2/20 | 0.37 |
| ▸ | NOS1 | P29475 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.36 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13826519 | 0.76 | ALDH1A1 (0.43) | MAPTALDH1A1 | |
| SCHEMBL14492992 | 0.75 | PRKCI (0.53) | PRKCIAKR1C3AKR1C2ALDH1A1NPC1 | |
| SCHEMBL12953268 | 0.73 | TDP1 (0.37) | CA1MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL17676671 | 0.72 | PRKCI (0.58) | PRKCIAKR1C3AKR1C2MAPTALDH1A1 | |
| SCHEMBL21700146 | 0.72 | PKM (0.50) | PRKCIAKR1C3AKR1C2CA1CA2 | |
| SCHEMBL9308545 | 0.72 | PRKCI (0.49) | PRKCIAKR1C3AKR1C2MAPTALDH1A1 | |
| SCHEMBL10872684 | 0.71 | CREBBP (0.58) | PRKCIAKR1C3AKR1C2ALDH1A1 | |
| SCHEMBL25527348 | 0.71 | PRKCI (0.49) | PRKCIAKR1C3AKR1C2MAPTALDH1A1 | |
| SCHEMBL14380951 | 0.70 | PGR (0.57) | NPC1RAB9A | |
| SCHEMBL27951759 | 0.70 | MAPT (0.71) | PRKCIAKR1C3AKR1C2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1429763-B1 | NOVEL LIGANDS FOR THE HisB10 Zn2+ SITES OF THE R-STATE INSULIN HEXAMER | NOVO NORDISK AS (DK) | 2007-05-30 | — | — | EP | disclosed |