SCHEMBL14529331

SCHEMBL14529331

Cc1cccc(S(=O)(=O)n2ccnc2)c1N

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.52
TSHR P16473 1/20 0.51
LMNA P02545 1/20 0.47
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
TP53 P04637 1/20 0.44
ALDH1A1 P00352 2/20 0.44
KDM4E B2RXH2 1/20 0.44
HPGD P15428 1/20 0.44
HSD17B10 Q99714 1/20 0.44
FABP4 P15090 1/20 0.40
CYP11B1 P15538 1/20 0.35
CYP11B2 P19099 1/20 0.35
PARP1 P09874 1/20 0.34
CD44 P16070 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4727160 0.84 HTT (0.57) HTTTSHRLMNAMEN1KMT2A
SCHEMBL28303262 0.82 HTT (0.49) HTTTSHRLMNAMEN1KMT2A
SCHEMBL14529097 0.81 CA1 (0.46) TSHRKMT2ASMN1; SMN2L3MBTL1ALDH1A1
SCHEMBL23699006 0.80 TSHR (0.58) HTTTSHRLMNAMEN1KMT2A
SCHEMBL4970093 0.79 HTT (0.49) HTTTSHRLMNAMEN1KMT2A
SCHEMBL14529330 0.73 CD44 (0.34) LMNAFABP4CD44
SCHEMBL10801457 0.73 SMN1; SMN2 (0.65) HTTTSHRLMNAMEN1KMT2A
SCHEMBL25350141 0.72 LMNA (0.51) HTTTSHRLMNAMEN1KMT2A
SCHEMBL3239413 0.71 TSHR (0.58) HTTTSHRLMNAMEN1KMT2A
SCHEMBL10798648 0.71 TSHR (0.58) HTTTSHRLMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007060220-A2 CYANOBENZENE COMPOUNDS FOR COMBATING ANIMAL PESTS BASF SE (DE) 2007-05-31 WO disclosed