Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | FABP4 | P15090 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | EDNRB | P24530 | 2/20 | 0.39 |
| ▸ | EDNRA | P25101 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10801457 | 0.85 | SMN1; SMN2 (0.65) | TSHRHTTLMNAKMT2ASMN1; SMN2 | |
| SCHEMBL3239413 | 0.82 | TSHR (0.58) | TSHRHTTLMNAKMT2ASMN1; SMN2 | |
| SCHEMBL4727160 | 0.78 | HTT (0.57) | TSHRHTTLMNAKMT2ASMN1; SMN2 | |
| SCHEMBL25350141 | 0.72 | LMNA (0.51) | TSHRHTTLMNAKMT2ASMN1; SMN2 | |
| SCHEMBL14529331 | 0.71 | HTT (0.52) | TSHRHTTLMNAKMT2ASMN1; SMN2 | |
| SCHEMBL841998 | 0.70 | TSHR (0.58) | TSHRHTTLMNAKMT2ASMN1; SMN2 | |
| SCHEMBL23699006 | 0.70 | TSHR (0.58) | TSHRHTTLMNAKMT2ASMN1; SMN2 | |
| SCHEMBL6102638 | 0.70 | KMT2A (0.79) | LMNAKMT2AALDH1A1 | |
| SCHEMBL217862 | 0.68 | TP53 (0.69) | TSHRHTTLMNAKMT2ASMN1; SMN2 | |
| SCHEMBL265203 | 0.68 | EDNRB (0.46) | TSHRLMNAKMT2ASMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4710509-A | IMIDAZOLE AND TRIAZOLE DERIVATIVES; FUNGICIDES | NIHON TOKUSHU NOYAKU SEIZO K. K. (JP) | 1987-12-01 | — | — | US | disclosed |
| EP-0173918-A2 | Substituted phenylsulfonyl azoles | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-03-12 | — | — | EP | disclosed |