Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 12/20 | 0.63 |
| ▸ | MMP2 | P08253 | 12/20 | 0.63 |
| ▸ | MMP9 | P14780 | 12/20 | 0.63 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.58 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.55 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.55 |
| ▸ | KDM1A | O60341 | 1/20 | 0.54 |
| ▸ | TOP2A | P11388 | 1/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.50 |
| ▸ | SNCA | P37840 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11707324 | 0.88 | GABBR2 (0.60) | MMP1MMP2MMP9GABBR2GABBR1 | |
| SCHEMBL11918436 | 0.87 | TRPV1 (0.52) | MMP1MMP2MMP9GABBR2GABBR1 | |
| SCHEMBL8567993 | 0.84 | GABBR2 (0.66) | GABBR2GABBR1MAOA | |
| SCHEMBL11059147 | 0.84 | GABBR2 (0.66) | GABBR2GABBR1MAOA | |
| SCHEMBL13407150 | 0.82 | GABBR2 (0.54) | MMP1MMP2MMP9GABBR2GABBR1 | |
| SCHEMBL11308327 | 0.81 | TNFRSF1A (0.64) | MMP1MMP2MMP9DEGS1TOP2A | |
| SCHEMBL9068680 | 0.81 | TNFRSF1A (0.64) | MMP1MMP2MMP9DEGS1TOP2A | |
| SCHEMBL14532945 | 0.80 | EGFR (0.51) | MMP1MMP2MMP9GABBR2GABBR1 | |
| SCHEMBL13675650 | 0.80 | MMP1 (0.77) | MMP1MMP2MMP9DEGS1TRPV1 | |
| SCHEMBL14701489 | 0.80 | MAPT (0.49) | MMP1MMP2MMP9TOP2ATRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007050985-A2 | MACROMOLECULAR ANTIOXIDANTS BASED ON STΞRICALLY HINDERED PHENOLIC PHOSPHITES | POLNOX CORPORATION (US) | 2007-05-03 | — | — | WO | disclosed |