Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 2/20 | 0.54 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.52 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 6/20 | 0.47 |
| ▸ | MAOA | P21397 | 4/20 | 0.47 |
| ▸ | MMP1 | P03956 | 4/20 | 0.47 |
| ▸ | MMP2 | P08253 | 4/20 | 0.47 |
| ▸ | MMP9 | P14780 | 4/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8567993 | 0.82 | GABBR2 (0.66) | GABBR2GABBR1PTGS2PTGS1TNFRSF1A | |
| SCHEMBL11059147 | 0.82 | GABBR2 (0.66) | GABBR2GABBR1PTGS2PTGS1TNFRSF1A | |
| SCHEMBL14529796 | 0.82 | MMP1 (0.63) | GABBR2GABBR1MAOAMMP1MMP2 | |
| Trans-4,4'-Dihydroxystilbene SCHEMBL11356852 | 0.81 | PTGS2 (0.77) | GABBR2GABBR1PTGS2PTGS1MAOB | |
| SCHEMBL9018395 | 0.79 | MMP1 (0.61) | TNFRSF1AMAOBMAOAMMP1MMP2 | |
| SCHEMBL13764739 | 0.77 | TNFRSF1A (0.65) | GABBR2GABBR1TNFRSF1AMAOBMAOA | |
| SCHEMBL8338249 | 0.77 | GABBR2 (0.62) | GABBR2GABBR1PTGS2PTGS1TNFRSF1A | |
| SCHEMBL8338252 | 0.77 | GABBR2 (0.62) | GABBR2GABBR1PTGS2PTGS1TNFRSF1A | |
| SCHEMBL11707324 | 0.76 | GABBR2 (0.60) | GABBR2GABBR1PTGS2PTGS1TNFRSF1A | |
| SCHEMBL4450576 | 0.75 | GABBR2 (0.68) | GABBR2GABBR1PTGS2PTGS1TNFRSF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7705075-B2 | Stabilized polyolefin compositions | POLNOX CORPORATION (US) | 2010-04-27 | — | — | US | disclosed |
| US-20080293856-A1 | Stabilized polyolefin compositions | POLNOX CORPORATION | 2008-11-27 | — | — | US | disclosed |