Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 2/20 | 0.49 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.46 |
| ▸ | AURKA | O14965 | 2/20 | 0.46 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.44 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.44 |
| ▸ | CHRNG | P07510 | 1/20 | 0.44 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.44 |
| ▸ | CHRND | Q07001 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | TTK | P33981 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8241160 | 0.87 | AURKA (0.49) | AURKBAURKACHRNB4CHRNA3CHRNB2 | |
| SCHEMBL13954745 | 0.86 | PTK6 (0.48) | PTK6AURKBAURKAMAPKAPK5LCK | |
| SCHEMBL14536944 | 0.85 | CHRNB4 (0.42) | AURKBAURKACHRNB4CHRNA3CHRNB2 | |
| SCHEMBL14538461 | 0.79 | PTK6 (0.48) | PTK6AURKBAURKAMAPKAPK5LCK | |
| SCHEMBL10169406 | 0.77 | MAPKAPK5 (0.57) | PTK6AURKBAURKAMAPKAPK5LCK | |
| SCHEMBL30138985 | 0.76 | MAPKAPK5 (0.62) | PTK6AURKBAURKAMAPKAPK5LCK | |
| SCHEMBL8246047 | 0.74 | FYN (0.52) | PTK6AURKBAURKAMAPKAPK5LCK | |
| SCHEMBL14536960 | 0.74 | MAPKAPK5 (0.62) | PTK6AURKBAURKAMAPKAPK5LCK | |
| SCHEMBL14538354 | 0.73 | PTK6 (0.52) | PTK6AURKBAURKAMAPKAPK5LCK | |
| SCHEMBL13954946 | 0.73 | PTK6 (0.53) | PTK6AURKBAURKAMAPKAPK5LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058873-A2 | IMIDAZOPYRAZINES AS CYCLIN DEPENTEND KINASE INHIBITORS | SCHERING CORPORATION (US) | 2007-05-24 | — | — | WO | disclosed |