Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.63 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | EBP | Q15125 | 1/20 | 0.50 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25358883 | 0.84 | SIGMAR1 (0.74) | SIGMAR1ADRA2AOPRM1OPRK1EBP | |
| SCHEMBL5315520 | 0.77 | SIGMAR1 (1.00) | SIGMAR1ADRA2AOPRM1OPRK1EBP | |
| SCHEMBL30623345 | 0.77 | SIGMAR1 (1.00) | SIGMAR1ADRA2AOPRM1OPRK1EBP | |
| SCHEMBL25358545 | 0.74 | SIGMAR1 (0.70) | SIGMAR1ADRA2AOPRM1OPRK1EBP | |
| Hydrochloric Acid SCHEMBL20955046 | 0.74 | SIGMAR1 (0.67) | SIGMAR1 | |
| SCHEMBL11860134 | 0.73 | PRCP (0.52) | SIGMAR1ADRA2AOPRM1OPRK1 | |
| SCHEMBL6820101 | 0.73 | SIGMAR1 (0.68) | SIGMAR1 | |
| SCHEMBL11859734 | 0.73 | SIGMAR1 (0.57) | SIGMAR1L3MBTL1 | |
| SCHEMBL25361546 | 0.73 | MEN1 (0.47) | SIGMAR1ADRA2A | |
| SCHEMBL26005046 | 0.73 | MEN1 (0.47) | SIGMAR1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007057775-A1 | SPIROPIPERIDINE DERIVATIVES | PFIZER LIMITED (GB) | 2007-05-24 | — | — | WO | disclosed |