Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 2/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.51 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.48 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.48 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.48 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.48 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11855307 | 0.89 | SIGMAR1 (0.53) | PRCPSIGMAR1GRIN2DGRIN3BDRD2 | |
| SCHEMBL11852054 | 0.79 | PRCP (0.42) | PRCPSIGMAR1ADRA2AHTR2AOPRM1 | |
| SCHEMBL11781081 | 0.79 | PRCP (0.42) | PRCPSIGMAR1ADRA2ADRD2OPRD1 | |
| SCHEMBL11680301 | 0.78 | OPRD1 (0.43) | PRCPSIGMAR1ADRA2AOPRD1 | |
| SCHEMBL11684907 | 0.77 | SIGMAR1 (0.70) | PRCPSIGMAR1ADRA2AOPRM1OPRD1 | |
| SCHEMBL11878975 | 0.75 | PRCP (0.39) | PRCPSIGMAR1ADRA2AOPRD1 | |
| SCHEMBL11684464 | 0.74 | PRCP (0.39) | PRCP | |
| SCHEMBL11684159 | 0.74 | SIGMAR1 (0.44) | SIGMAR1HTR2AOPRD1 | |
| SCHEMBL14530329 | 0.73 | SIGMAR1 (0.63) | SIGMAR1ADRA2AOPRM1OPRK1 | |
| SCHEMBL11853169 | 0.73 | PRCP (0.45) | PRCPSIGMAR1OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3959475-A | ANTIDEPRESSANT, TRANQUILIZER, ANALGESIC | AMERICAN HOECHST CORPORATION (US) | 1976-05-25 | — | — | US | disclosed |