Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | F10 | P00742 | 1/20 | 0.30 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20082452 | 0.94 | PARP1 (0.33) | PARP1F2F10PRSS1 | |
| SCHEMBL13954 | 0.85 | MC4R (0.39) | PARP1 | |
| SCHEMBL14145 | 0.83 | MAPT (0.31) | PARP1ALDH1A1F2F10PRSS1 | |
| SCHEMBL20019746 | 0.83 | PARP1 (0.31) | PARP1F2F10PRSS1 | |
| SCHEMBL14315402 | 0.83 | PARP1 (0.31) | PARP1F2F10PRSS1 | |
| SCHEMBL20019754 | 0.82 | PARP1 (0.32) | PARP1F2F10PRSS1 | |
| SCHEMBL12075212 | 0.82 | OPRM1 (0.31) | PARP1F2F10PRSS1 | |
| SCHEMBL14177 | 0.82 | PARP1 (0.30) | PARP1F2F10PRSS1 | |
| SCHEMBL20019825 | 0.82 | PARP1 (0.30) | PARP1F2F10PRSS1 | |
| SCHEMBL20019810 | 0.81 | HDAC3 (0.33) | PARP1ALDH1A1F2F10PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10815238-B2 | Antimicrobial compounds and methods of making and using the same | BioVersys AG (CH) | 2020-10-27 | — | — | US | disclosed |
| US-20190284190-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | BioVersys AG (CH) | 2019-09-19 | — | — | US | disclosed |
| EP-2488525-B1 | ANTIMICROBIAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | MELINTA THERAPEUTICS INC (US) | 2018-04-25 | — | — | EP | disclosed |
| EP-2697229-B1 | ANTIMICROBIAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | MELINTA THERAPEUTICS INC (US) | 2018-04-04 | — | — | EP | disclosed |
| US-20160031893-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | BioVersys AG (CH) | 2016-02-04 | — | — | US | disclosed |
| US-9193731-B2 | Antimicrobial compounds and methods of making and using the same | MELINTA THERAPEUTICS, INC. (US) | 2015-11-24 | — | — | US | disclosed |
| US-20120220566-A1 | Antimicrobial Compounds and Methods of Making and Using the Same | RIB-X PHARMACEUTICALS, INC. (US) | 2012-08-30 | — | — | US | disclosed |
| WO-2011047319-A2 | ANTIMICROBIAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | RIB-X PHARMACEUTICALS, INC. (US) | 2011-04-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120220566-A1 | Antimicrobial Compounds and Methods of Making and Using the Same | MPO, LPO, CAT | PARP1 1324/4885ALDH1A1 1117/4885F2 2029/4885 |
| US-20190284190-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | MPO, LPO, CAT | PARP1 1384/4885ALDH1A1 1218/4885F2 1772/4885 |
| US-20160031893-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | MPO, LPO, CAT | PARP1 1324/4885ALDH1A1 1117/4885F2 2029/4885 |
| US-10815238-B2 | Antimicrobial compounds and methods of making and using the same | MPO, LPO, CAT | PARP1 1384/4885ALDH1A1 1218/4885F2 1772/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.