SCHEMBL14533005

SCHEMBL14533005

CCCS(=O)(=O)N1CN(S(=O)(=O)CCC)CN(S(=O)(=O)CCC)C1

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.43
KDM4E B2RXH2 6/20 0.41
GLA P06280 2/20 0.41
GAA P10253 1/20 0.41
PKM P14618 1/20 0.41
ALDH1A1 P00352 4/20 0.40
LMNA P02545 2/20 0.40
MAPT P10636 2/20 0.40
TSHR P16473 2/20 0.40
HSD17B10 Q99714 1/20 0.40
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
USP2 O75604 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
ALOX15 P16050 1/20 0.36
KMT2A Q03164 1/20 0.36
POLB P06746 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14951100 0.97 L3MBTL1 (0.42) L3MBTL1KDM4EGLAGAAPKM
SCHEMBL21954013 0.85 L3MBTL1 (0.36) L3MBTL1KDM4EGLAGAAPKM
SCHEMBL23555007 0.83 L3MBTL1 (0.56) L3MBTL1KDM4EGLAGAAPKM
SCHEMBL26201832 0.82 POLB (0.37) L3MBTL1KDM4EGAAPKMALDH1A1
SCHEMBL16218316 0.82 MAPT (0.35) L3MBTL1KDM4EGLAGAAPKM
SCHEMBL178417 0.79 L3MBTL1 (0.49) L3MBTL1KDM4EGLAGAAPKM
SCHEMBL31030375 0.79 L3MBTL1 (0.49) L3MBTL1KDM4EGLAGAAPKM
SCHEMBL4277869 0.77 L3MBTL1 (0.47) L3MBTL1KDM4EGLAGAAPKM
SCHEMBL10192197 0.75 L3MBTL1 (0.50) L3MBTL1KDM4EGLAGAAPKM
SCHEMBL27326295 0.75 ALDH1A1 (0.46) L3MBTL1KDM4EGLAGAAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9578944-B2 Compositions and methods for altering the appearance of hair L'OREAL (FR) 2017-02-28 US disclosed
US-9578944-B2 Compositions and methods for altering the appearance of hair L'OREAL (FR) 2017-02-28 US disclosed
US-9565916-B2 Compositions and methods for altering the appearance of hair L'OREAL (FR) 2017-02-14 US disclosed
US-9565915-B2 Compositions and methods for altering the appearance of hair L'OREAL (FR) 2017-02-14 US disclosed
US-9566221-B2 Methods for altering the color and appearance of hair L'OREAL (FR) 2017-02-14 US disclosed
US-20140311517-A1 COMPOSITIONS AND METHODS FOR ALTERING THE APPEARANCE OF HAIR L'OREAL (FR) 2014-10-23 US disclosed
US-20140305464-A1 COMPOSITIONS AND METHODS FOR ALTERING THE APPEARANCE OF HAIR L'OREAL (FR) 2014-10-16 US disclosed
US-20140305464-A1 COMPOSITIONS AND METHODS FOR ALTERING THE APPEARANCE OF HAIR L'OREAL (FR) 2014-10-16 US disclosed
US-7220286-B2 Cationic direct triazo dyes, dye composition comprising them and process for dyeing keratin fibres using it L'OREAL SA (FR) 2007-05-22 US disclosed