Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14502797 | 0.85 | ALDH1A1 (0.32) | MAPTALDH1A1KDM4ELMNAHTT | |
| SCHEMBL14533005 | 0.82 | L3MBTL1 (0.43) | MAPTTSHRL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL14951100 | 0.80 | L3MBTL1 (0.42) | MAPTTSHRL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL16186774 | 0.71 | MAPT (0.32) | MAPTTSHRL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL21954013 | 0.69 | L3MBTL1 (0.36) | MAPTTSHRL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL23555007 | 0.68 | L3MBTL1 (0.56) | MAPTTSHRL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL26201832 | 0.67 | POLB (0.37) | MAPTTSHRL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL178417 | 0.65 | L3MBTL1 (0.49) | MAPTTSHRL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL31030375 | 0.65 | L3MBTL1 (0.49) | MAPTTSHRL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL4277869 | 0.63 | L3MBTL1 (0.47) | TSHRL3MBTL1ALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9565915-B2 | Compositions and methods for altering the appearance of hair | L'OREAL (FR) | 2017-02-14 | — | — | US | disclosed |
| US-9566221-B2 | Methods for altering the color and appearance of hair | L'OREAL (FR) | 2017-02-14 | — | — | US | disclosed |
| US-20150265513-A1 | METHODS FOR ALTERING THE COLOR AND APPEARANCE OF HAIR | L'OREAL (FR) | 2015-09-24 | — | — | US | disclosed |
| US-20140326270-A1 | COMPOSITIONS AND METHODS FOR ALTERING THE APPEARANCE OF HAIR | L'OREAL (FR) | 2014-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150265513-A1 | METHODS FOR ALTERING THE COLOR AND APPEARANCE OF HAIR | COXFA4L2, TYR, COX5A | MAPT 2207/4885TSHR 4564/4885L3MBTL1 4517/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.