Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH2 | P48735 | 8/20 | 0.70 |
| ▸ | CAMK1D | Q8IU85 | 11/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5386983 | 0.91 | IDH2 (0.56) | IDH2CAMK1DMAPT | |
| SCHEMBL30568819 | 0.83 | IDH2 (1.00) | IDH2CAMK1DMAPT | |
| SCHEMBL14440842 | 0.81 | IDH2 (0.61) | IDH2CAMK1DMAPT | |
| SCHEMBL28459472 | 0.80 | IDH2 (0.90) | IDH2CAMK1DMAPT | |
| SCHEMBL5390801 | 0.80 | IDH2 (0.72) | IDH2MAPT | |
| SCHEMBL5462440 | 0.78 | IDH2 (0.56) | IDH2CAMK1D | |
| SCHEMBL14533274 | 0.77 | IDH2 (0.63) | IDH2CAMK1DMAPT | |
| SCHEMBL5380616 | 0.77 | ADRA1D (0.47) | IDH2CAMK1D | |
| SCHEMBL14533275 | 0.75 | PTGS2 (0.51) | IDH2CAMK1D | |
| SCHEMBL14440330 | 0.75 | POLB (0.54) | IDH2CAMK1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223759-B2 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2007-05-29 | — | — | US | disclosed |