Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 7/20 | 0.35 |
| ▸ | CTSL | P07711 | 3/20 | 0.34 |
| ▸ | CTSB | P07858 | 3/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.34 |
| ▸ | CTSH | P09668 | 2/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4302074 | 0.79 | CPA1 (0.37) | L3MBTL1 | |
| SCHEMBL5492736 | 0.78 | CYP2D6 (0.35) | — | |
| SCHEMBL7686445 | 0.77 | EPHX2 (0.39) | EPHX2GLA | |
| SCHEMBL13610018 | 0.73 | CTSK (0.44) | CTSKCTSLCTSBEPHX2CTSH | |
| SCHEMBL14111950 | 0.73 | CTSK (0.41) | CTSKCTSLCTSBEPHX2CTSH | |
| SCHEMBL5497112 | 0.73 | ANPEP (0.34) | — | |
| SCHEMBL17748406 | 0.72 | CPA1 (0.47) | L3MBTL1 | |
| SCHEMBL4321183 | 0.72 | CPA1 (0.33) | L3MBTL1 | |
| SCHEMBL14392297 | 0.72 | LTA4H (0.38) | CTSKCTSLCTSBEPHX2CTSH | |
| SCHEMBL232250 | 0.69 | CYP2D6 (0.46) | CTSKCTSLCTSBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0937032-B1 | SUBSTITUTED GAMMA AMINOBUTYRIC ACIDS AS PHARMACEUTICAL AGENTS | WARNER LAMBERT CO (US) | 2007-05-09 | — | — | EP | disclosed |