Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | KCNA3 | P22001 | 4/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL231007 | 0.91 | CRHR1 (0.36) | ALDH1A1GAAHSD17B10KDM4ETHRB | |
| SCHEMBL14535345 | 0.91 | LMNA (0.37) | ALDH1A1GAAHSD17B10KDM4ETHRB | |
| SCHEMBL14535493 | 0.89 | LMNA (0.33) | LMNAKMT2AMEN1NPC1KCNA3 | |
| SCHEMBL14535492 | 0.89 | ALDH1A1 (0.40) | ALDH1A1GAAHSD17B10KDM4ETHRB | |
| SCHEMBL14535349 | 0.87 | KMT2A (0.35) | ALDH1A1GAAHSD17B10KDM4ELMNA | |
| SCHEMBL14535341 | 0.87 | KCNA3 (0.37) | ALDH1A1GAAHSD17B10KDM4ETHRB | |
| SCHEMBL14535343 | 0.86 | KCNA3 (0.35) | LMNAKMT2AMEN1NPC1KCNA3 | |
| SCHEMBL14535347 | 0.86 | LMNA (0.32) | LMNAKMT2AMEN1NPC1 | |
| SCHEMBL14535346 | 0.86 | LMNA (0.40) | LMNAKMT2AMEN1NPC1KCNA3 | |
| SCHEMBL14535348 | 0.85 | KMT2A (0.34) | ALDH1A1GAAHSD17B10KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007057407-A2 | INSECTICIDAL METHODS USING 3-AMINO-1,2-BENZISOTHIAZOLE DERIVATIVES | BASF SE (DE) | 2007-05-24 | — | — | WO | disclosed |