Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7816915 | 0.78 | ALDH1A1 (0.48) | KMT2AGLAALDH1A1SMN1; SMN2PKM | |
| SCHEMBL3031214 | 0.77 | PPARG (0.48) | ALDH1A1SMN1; SMN2PKMIDO1ACE | |
| SCHEMBL3026074 | 0.77 | PPARG (0.48) | ALDH1A1SMN1; SMN2PKMIDO1ACE | |
| SCHEMBL3029296 | 0.77 | PPARG (0.51) | ALDH1A1SMN1; SMN2PKMIDO1ACE | |
| SCHEMBL7827480 | 0.76 | GAA (0.53) | KMT2AGLAALDH1A1SMN1; SMN2PKM | |
| SCHEMBL3416831 | 0.76 | ACE (0.46) | KMT2AGLAALDH1A1SMN1; SMN2PKM | |
| Hydrochloric Acid SCHEMBL3416832 | 0.75 | IDO1 (0.46) | KMT2AGLAALDH1A1SMN1; SMN2PKM | |
| Hydrochloric Acid SCHEMBL3416827 | 0.75 | IDO1 (0.46) | KMT2AGLAALDH1A1SMN1; SMN2PKM | |
| SCHEMBL7352199 | 0.75 | SMN1; SMN2 (0.48) | KMT2AALDH1A1SMN1; SMN2PKMIDO1 | |
| SCHEMBL9166221 | 0.75 | PPARA (0.50) | ALDH1A1SMN1; SMN2PKMIDO1ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8765955-B2 | Asymmetric aldol additions using bifunctional cinchona-alkaloid-based catalysts | BRANDEIS UNIVERSITY (US) | 2014-07-01 | — | — | US | disclosed |
| US-20070112199-A1 | Asymmetric aldol additions using bifunctional cinchona-alkaloid-based catalysts | BRANDEIS UNIVERSITY (US) | 2007-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070112199-A1 | Asymmetric aldol additions using bifunctional cinchona-alkaloid-based catalysts | AKR1C2, AKR1A1, AKR1B1 | KMT2A 622/4885GLA 2341/4885ALDH1A1 45/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.