Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | ACE | P12821 | 2/20 | 0.47 |
| ▸ | LDHA | P00338 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7352199 | 0.88 | SMN1; SMN2 (0.48) | PPARAPPARGACELDHAGAA | |
| SCHEMBL9171687 | 0.82 | CYP2C19 (0.50) | PPARAPPARGACEALDH1A1SMN1; SMN2 | |
| SCHEMBL3029296 | 0.78 | PPARG (0.51) | PPARAPPARGACELDHAGAA | |
| SCHEMBL3801397 | 0.78 | LDHA (0.53) | PPARAPPARGLDHASMN1; SMN2FFAR1 | |
| SCHEMBL5757662 | 0.78 | LDHA (0.49) | PPARAPPARGACELDHAIDO1 | |
| SCHEMBL4413232 | 0.77 | LDHA (0.51) | PPARAPPARGLDHAALDH1A1SMN1; SMN2 | |
| SCHEMBL498480 | 0.77 | CYP1A2 (0.67) | PPARAPPARGACELDHAGAA | |
| SCHEMBL28246723 | 0.77 | LDHA (0.51) | PPARAPPARGLDHAALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6574400 | 0.76 | IDO1 (0.49) | PPARAPPARGACELDHAIDO1 | |
| SCHEMBL6085105 | 0.76 | GAA (0.53) | PPARAPPARGACEGAAIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0455833-B1 | AMINO ACID DERIVATIVE | SANTEN PHARMACEUTICAL CO LTD (JP) | 1995-04-19 | — | — | EP | disclosed |
| US-5214181-A | Immunodeficiency and autoimmune disease treatment | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1993-05-25 | — | — | US | disclosed |
| EP-0455833-A1 | AMINO ACID DERIVATIVE | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1991-11-13 | — | — | EP | disclosed |