SCHEMBL14537286

SCHEMBL14537286

Cc1ccc(N(c2ccc(C)cc2)c2ccc(/C=C/c3ccc(N(c4ccc(C)cc4)c4ccc5c6ccc(N(c7ccc(C)cc7)c7ccc(/C=C/c8ccc(N(c9ccc(C)cc9)c9ccc(C)cc9)cc8)cc7)c7cccc(c8cccc4c85)c76)cc3)cc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 7/20 0.38
APP P05067 3/20 0.37
RELA Q04206 2/20 0.35
TRPM8 Q7Z2W7 1/20 0.34
RAB9A P51151 3/20 0.33
NPC1 O15118 2/20 0.33
MEN1 O00255 2/20 0.33
APOBEC3A P31941 2/20 0.33
KMT2A Q03164 2/20 0.33
APOBEC3G Q9HC16 2/20 0.33
ALOX5 P09917 1/20 0.33
PTGS1 P23219 1/20 0.33
PTGS2 P35354 1/20 0.33
MAT2A P31153 1/20 0.33
KCNH2 Q12809 1/20 0.33
KDM4E B2RXH2 1/20 0.33
CASP3 P42574 1/20 0.33
SENP8 Q96LD8 1/20 0.33
SENP7 Q9BQF6 1/20 0.33
SENP6 Q9GZR1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14099226 0.98 NFE2L2 (0.39) NFE2L2APPRELATRPM8RAB9A
SCHEMBL6770761 0.98 NFE2L2 (0.39) NFE2L2APPRELATRPM8RAB9A
SCHEMBL14099225 0.98 NFE2L2 (0.39) NFE2L2APPRELATRPM8RAB9A
SCHEMBL6297043 0.98 NFE2L2 (0.39) NFE2L2APPRELATRPM8RAB9A
SCHEMBL14537302 0.97 NFE2L2 (0.38) NFE2L2APPRELATRPM8RAB9A
SCHEMBL6775821 0.94 TRPM8 (0.41) NFE2L2APPRELATRPM8RAB9A
SCHEMBL21090037 0.94 RELA (0.44) NFE2L2APPRELATRPM8RAB9A
SCHEMBL17879391 0.93 RELA (0.42) NFE2L2APPRELATRPM8RAB9A
SCHEMBL6771479 0.93 NFE2L2 (0.36) NFE2L2APPRELATRPM8RAB9A
SCHEMBL26549662 0.93 RELA (0.42) NFE2L2APPRELATRPM8RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8349472-B2 Organic electroluminescence device SAMSUNG DISPLAY CO., LTD. (KR) 2013-01-08 US disclosed
US-8349472-B2 Organic electroluminescence device SAMSUNG DISPLAY CO., LTD. (KR) 2013-01-08 US disclosed