SCHEMBL145373

SCHEMBL145373

O=Cc1ccc(OCCO)cc1

nearest known ligand 0.58

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.58
SMN1; SMN2 Q16637 4/20 0.58
MAPT P10636 2/20 0.58
HPGD P15428 2/20 0.58
LMNA P02545 2/20 0.58
RECQL P46063 1/20 0.54
GAA P10253 1/20 0.50
NR1I2 O75469 1/20 0.48
CYP2A6 P11509 1/20 0.48
KMT2A Q03164 1/20 0.47
KDM4E B2RXH2 2/20 0.46
RAB9A P51151 1/20 0.45
CYP3A4 P08684 1/20 0.44
DRD1 P21728 1/20 0.44
ALDH1A3 P47895 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7213903 0.96 ALDH1A1 (0.54) ALDH1A1SMN1; SMN2MAPTHPGDLMNA
Isopropyl Alcohol SCHEMBL2167428 0.91 ALDH1A1 (0.54) ALDH1A1SMN1; SMN2MAPTHPGDLMNA
SCHEMBL945454 0.90 ALDH1A1 (0.61) ALDH1A1SMN1; SMN2MAPTHPGDLMNA
SCHEMBL3861084 0.89 APP (0.53) ALDH1A1SMN1; SMN2MAPTHPGDLMNA
SCHEMBL4595052 0.89 APP (0.53) ALDH1A1SMN1; SMN2MAPTHPGDLMNA
SCHEMBL2229143 0.89 APP (0.53) ALDH1A1SMN1; SMN2MAPTHPGDLMNA
SCHEMBL7613986 0.88 ALDH1A1 (0.59) ALDH1A1SMN1; SMN2MAPTHPGDLMNA
SCHEMBL851166 0.87 ALDH1A1 (0.66) ALDH1A1SMN1; SMN2MAPTHPGDLMNA
SCHEMBL2222324 0.86 ALDH1A1 (0.57) ALDH1A1SMN1; SMN2MAPTHPGDLMNA
SCHEMBL12933662 0.86 ALDH1A1 (0.57) ALDH1A1SMN1; SMN2MAPTHPGDLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 537 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118496253-A TEMPO-fluoboric fluorescence photosensitizer, synthesis method and application thereof in perovskite battery 合肥大学 2024-08-16 CN claimed
CN-115160752-B Polylactic acid composite material for mulching film and application thereof 山西生物质新材料产业研究院有限公司 2023-08-01 CN claimed
US-11672785-B2 Tetrahydro-1H-pyrido [3,4-b]indole anti-estrogenic drugs OLEMA PHARMACEUTICALS, INC. (US) 2023-06-13 US claimed
US-20220370421-A1 TETRAHYDRO-1H-PYRIDO [3,4-b]INDOLE ANTI-ESTROGENIC DRUGS OLEMA PHARMACEUTICALS, INC. 2022-11-24 US claimed
CN-115160752-A Polylactic acid composite material for mulching film and application thereof 山西生物质新材料产业研究院有限公司 2022-10-11 CN claimed
CN-114075320-A Fluorescent waterborne polyurethane with adjustable luminescent color and preparation method thereof 四川大学 2022-02-22 CN claimed
CN-113355028-A Light-cured material, display panel and preparation method thereof 深圳市华星光电半导体显示技术有限公司 2021-09-07 CN claimed
CN-103467746-B A kind of amphipathic nature polyalcohol and preparation method thereof CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY CHINESE ACADEMY OF SCIENCES (CN) 2015-12-09 CN claimed
US-8889896-B2 Process for the preparation of bazedoxifene acetate and intermediates thereof Divi's Laboratories, Ltd. (IN) 2014-11-18 US claimed
CN-103467746-A Amphiphilic polymer and preparing method thereof CHANGCHUN APPLIED CHEMISTRY 2013-12-25 CN claimed
US-20130289296-A1 NOVEL PROCESS FOR THE PREPARATION OF BAZEDOXIFENE ACETATE AND INTERMEDIATES THEREOF DIVI'S LABORATORIES LTD. (IN) 2013-10-31 US claimed
US-20120330008-A1 NOVEL PROCESS FOR THE PREPARATION OF BAZEDOXIFENE ACETATE AND INTERMEDIATES THEREOF DIVI'S LABORATORIES LIMITED (IN) 2012-12-27 US claimed
US-20070130702-A1 Dyeing process using a specific compound containing active methylene and a compound chosen from a specific aldehyde, a specific ketone, a quinone and a diiminoisoindoline or 3-aminoisoindolone derivative L'OREAL S.A. 2007-06-14 US claimed
US-7204857-B1 Dyeing method using a specific active methylene compound and a compound selected among a specific aldehyde, a specific ketone, a quinone and a di-imino-isoindoline or 3-amino-isoindolone derivative L'OREAL S.A. (FR) 2007-04-17 US claimed
US-6635090-B1 Dyeing method using a specific cationic derivative and a compound selected among a specific aldehyde, a specific ketone, a quinone and a di-imino-isoindoline or 3-amino-isoindolone derivative L'OREAL, S.A. (FR) 2003-10-21 US claimed
US-6458168-B1 Hair dyeing method using an aliphatic cationic amine and compound chosen from an aldehyde, a ketone, a quinone, a di-imino-isoindoline, and a 3-aminoisoindolone derivative L'OREAL S.A. (FR) 2002-10-01 US claimed
US-6451067-B1 HAIR DYE MIXTURE L'OREAL S.A. (FR) 2002-09-17 US claimed
EP-4731691-A1 CURABLE COMPOSITION HAVING AN ALDEHYDE-FUNCTIONAL POLYMER Sika Technology AG (CH) 2026-04-29 EP disclosed
US-4053415-A UNSATURATED POLYESTER ETHER HAVING A PHOTOCROSSLINKABLE MOIETY FUJI PHOTO FILM CO., LTD. (JA) 1977-10-11 US disclosed
US-3994907-A Coumarin derivatives, their preparation and their use as optical brightening agents PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1976-11-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120330008-A1 NOVEL PROCESS FOR THE PREPARATION OF BAZEDOXIFENE ACETATE AND INTERMEDIATES THEREOF CYP19A1, HSD17B11, SULT1E1 ALDH1A1 171/4885SMN1; SMN2 2325/4885MAPT 4168/4885
US-11672785-B2 Tetrahydro-1H-pyrido [3,4-b]indole anti-estrogenic drugs ESR1, CYP19A1, HSD17B11 ALDH1A1 1842/4885SMN1; SMN2 2933/4885MAPT 170/4885
US-20070130702-A1 Dyeing process using a specific compound containing active methylene and a compound chosen from a specific aldehyde, a specific ketone, a quinone and a diiminoisoindoline or 3-aminoisoindolone derivative KRT18, NDUFB5, NDUFB7 ALDH1A1 83/4885SMN1; SMN2 3654/4885MAPT 685/4885
US-20130289296-A1 NOVEL PROCESS FOR THE PREPARATION OF BAZEDOXIFENE ACETATE AND INTERMEDIATES THEREOF CYP19A1, HSD17B11, SULT1E1 ALDH1A1 171/4885SMN1; SMN2 2325/4885MAPT 4168/4885
US-20220370421-A1 TETRAHYDRO-1H-PYRIDO [3,4-b]INDOLE ANTI-ESTROGENIC DRUGS ESR1, CYP19A1, HSD17B11 ALDH1A1 1842/4885SMN1; SMN2 2933/4885MAPT 170/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.