Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 6/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10269895 | 0.88 | TAAR1 (0.43) | TAAR1ESR2TNKS2PDE3BPDE3A | |
| SCHEMBL17010798 | 0.81 | LIPG (0.44) | TAAR1ESR2TNKS2PDE3BPDE3A | |
| SCHEMBL14537751 | 0.81 | TAAR1 (0.40) | TAAR1ESR2TNKS2PDE3BPDE3A | |
| SCHEMBL18970438 | 0.73 | TAAR1 (0.55) | TAAR1ESR2TNKS2PDE3BPDE3A | |
| SCHEMBL2297807 | 0.72 | TAAR1 (0.47) | TAAR1ESR2TNKS2PDE3BPDE3A | |
| SCHEMBL18970412 | 0.71 | TAAR1 (0.53) | TAAR1ESR2TNKS2PGRACHE | |
| SCHEMBL10269575 | 0.70 | LIPG (0.45) | TAAR1ESR2TNKS2PGRCYP11B2 | |
| SCHEMBL18970517 | 0.69 | TAAR1 (0.50) | TAAR1ESR2TNKS2PGRACHE | |
| SCHEMBL18970556 | 0.69 | TAAR1 (0.50) | TAAR1ESR2TNKS2PGRACHE | |
| SCHEMBL257773 | 0.69 | TNKS2 (0.56) | TAAR1ESR2TNKS2PGRACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9108989-B2 | Inhibitors of fatty acid amide hydrolase | INFINITY PHARMACEUTICALS, INC. (US) | 2015-08-18 | — | — | US | disclosed |
| US-8349814-B2 | Inhibitors of fatty acid amide hydrolase | INFINITY PHARMACEUTICALS, INC. (US) | 2013-01-08 | — | — | US | disclosed |