Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 5/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.35 |
| ▸ | GABRE | P78334 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL258030 | 0.88 | TAAR1 (0.42) | TAAR1ESR2TNKS2CA12CA9 | |
| SCHEMBL14537752 | 0.81 | TAAR1 (0.41) | TAAR1ESR2TNKS2PGRPDE3B | |
| SCHEMBL17010798 | 0.79 | LIPG (0.44) | TAAR1ESR2TNKS2PGRPDE3B | |
| SCHEMBL12261266 | 0.79 | NPC1 (0.37) | PDE3BPDE3AACHECYP3A4PDK2 | |
| SCHEMBL12062032 | 0.74 | NFE2L2 (0.36) | CA9PDE3A | |
| SCHEMBL18970438 | 0.71 | TAAR1 (0.55) | TAAR1ESR2TNKS2PGRPDE3B | |
| SCHEMBL2297807 | 0.71 | TAAR1 (0.47) | TAAR1ESR2TNKS2CA12CA9 | |
| SCHEMBL15976054 | 0.71 | NFE2L2 (0.33) | ACHE | |
| SCHEMBL18970412 | 0.70 | TAAR1 (0.53) | TAAR1ESR2TNKS2PGRACHE | |
| SCHEMBL10269575 | 0.69 | LIPG (0.45) | TAAR1ESR2TNKS2PGRCYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9108989-B2 | Inhibitors of fatty acid amide hydrolase | INFINITY PHARMACEUTICALS, INC. (US) | 2015-08-18 | — | — | US | disclosed |
| US-8349814-B2 | Inhibitors of fatty acid amide hydrolase | INFINITY PHARMACEUTICALS, INC. (US) | 2013-01-08 | — | — | US | disclosed |