Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 5/20 | 0.44 |
| ▸ | LPL | P06858 | 4/20 | 0.44 |
| ▸ | PGR | P06401 | 6/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10269575 | 0.90 | LIPG (0.45) | LIPGLPLPGRTAAR1ESR2 | |
| SCHEMBL14696435 | 0.86 | LIPG (0.45) | LIPGLPL | |
| SCHEMBL20904793 | 0.85 | LIPG (0.46) | LIPGLPLPGRTAAR1ESR2 | |
| SCHEMBL13830608 | 0.84 | LIPG (0.59) | LIPGLPLPGRTNKS2 | |
| SCHEMBL6311907 | 0.82 | LPL (0.49) | LIPGLPLPDE3A | |
| SCHEMBL31605738 | 0.82 | LPL (0.49) | LIPGLPLPDE3A | |
| SCHEMBL29399706 | 0.81 | LIPG (0.40) | LIPGLPLPGRTAAR1ESR2 | |
| SCHEMBL14537752 | 0.81 | TAAR1 (0.41) | PGRTAAR1ESR2TNKS2PDE3B | |
| SCHEMBL14537751 | 0.79 | TAAR1 (0.40) | PGRTAAR1ESR2TNKS2PDE3B | |
| SCHEMBL12261264 | 0.79 | LIPG (0.41) | LIPGLPLPGRPDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9108989-B2 | Inhibitors of fatty acid amide hydrolase | INFINITY PHARMACEUTICALS, INC. (US) | 2015-08-18 | — | — | US | disclosed |