Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PPP5C | P53041 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11981972 | 1.00 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1TDP1PPP5CTSHR | |
| SCHEMBL10218188 | 0.85 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1TDP1PPP5CTSHR | |
| SCHEMBL13086088 | 0.84 | SMN1; SMN2 (0.32) | SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL16556717 | 0.80 | ALDH1A1 (0.46) | SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL13086175 | 0.74 | SMN1; SMN2 (0.30) | SMN1; SMN2 | |
| SCHEMBL17087049 | 0.72 | PPP5C (0.50) | SMN1; SMN2ALDH1A1TDP1PPP5CTSHR | |
| SCHEMBL18391823 | 0.72 | PPP5C (0.50) | SMN1; SMN2ALDH1A1TDP1PPP5CTSHR | |
| SCHEMBL21391306 | 0.71 | — | — | |
| SCHEMBL13935548 | 0.70 | ALDH1A1 (0.55) | SMN1; SMN2ALDH1A1TDP1TSHR | |
| SCHEMBL24238134 | 0.70 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1TDP1PPP5CPDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8772450-B2 | Beta-amino acids | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2014-07-08 | — | — | US | disclosed |
| US-20070123709-A1 | Beta-amino acids | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070123709-A1 | Beta-amino acids | BCAT1, MARCKS, YWHAZ | SMN1; SMN2 4026/4885ALDH1A1 4837/4885TDP1 4081/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.