Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.67 |
| ▸ | MAOA | P21397 | 2/20 | 0.67 |
| ▸ | ACHE | P22303 | 3/20 | 0.60 |
| ▸ | MIF | P14174 | 5/20 | 0.58 |
| ▸ | BCHE | P06276 | 1/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.53 |
| ▸ | TNF | P01375 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | STK17B | O94768 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1453994 | 1.00 | MAOB (0.67) | MAOBMAOAACHEMIFBCHE | |
| SCHEMBL6681374 | 0.87 | MAOB (0.73) | MAOBMAOAACHEMIFBCHE | |
| SCHEMBL3801973 | 0.87 | MAOB (0.73) | MAOBMAOAACHEMIFBCHE | |
| SCHEMBL16312876 | 0.87 | MAOB (0.73) | MAOBMAOAACHEMIFBCHE | |
| SCHEMBL30298462 | 0.87 | MAOB (0.73) | MAOBMAOAACHEMIFBCHE | |
| SCHEMBL9168685 | 0.85 | MAOB (0.66) | MAOBMAOAACHEMIFBCHE | |
| SCHEMBL9166995 | 0.85 | MAOB (0.66) | MAOBMAOAACHEMIFBCHE | |
| SCHEMBL9166494 | 0.82 | MAOB (0.62) | MAOBMAOAACHEMIFBCHE | |
| SCHEMBL51712 | 0.80 | MAOB (1.00) | MAOBMAOAACHEMIFBCHE | |
| SCHEMBL51711 | 0.80 | MAOB (1.00) | MAOBMAOAACHEMIFBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110190492-A1 | DIAGNOSTIC PROBE FOR CONFORMATION DISEASE | TOHOKU UNIVERSITY (JP) | 2011-08-04 | — | — | US | disclosed |
| US-7910579-B2 | Benzoxazole derivatives | TOHOKU UNIVERSITY (JP) | 2011-03-22 | — | — | US | disclosed |
| US-20100021385-A1 | BENZOXAZOLE DERIVATIVES | TOHOKU UNIVERSITY (JP) | 2010-01-28 | — | — | US | disclosed |
| EP-2103611-A1 | BENZOXAZOLE DERIVATIVES | Tohoku University (JP) | 2009-09-23 | — | — | EP | disclosed |
| US-20090185975-A1 | DIAGNOSTIC PROBE FOR CONFORMATION DISEASE | TOHOKU UNIVERSITY (JP) | 2009-07-23 | — | — | US | disclosed |
| EP-1967517-A1 | PROBE FOR DIAGNOSIS OF CONFORMATIONAL DISEASE | TOHOKU UNIVERSITY (JP) | 2008-09-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090185975-A1 | DIAGNOSTIC PROBE FOR CONFORMATION DISEASE | TARDBP, LMNA, PMP22 | MAOB 2710/4885MAOA 3430/4885ACHE 2033/4885 |
| US-20100021385-A1 | BENZOXAZOLE DERIVATIVES | CBX7, KIT, BMX | MAOB 2087/4885MAOA 1977/4885ACHE 3046/4885 |
| US-20110190492-A1 | DIAGNOSTIC PROBE FOR CONFORMATION DISEASE | TARDBP, LMNA, PMP22 | MAOB 2710/4885MAOA 3430/4885ACHE 2033/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.