Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.65 |
| ▸ | RAB9A | P51151 | 7/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.65 |
| ▸ | HTT | P42858 | 3/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | CA12 | O43570 | 3/20 | 0.59 |
| ▸ | CA1 | P00915 | 3/20 | 0.59 |
| ▸ | CA2 | P00918 | 3/20 | 0.59 |
| ▸ | CA9 | Q16790 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | KLK7 | P49862 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30664572 | 0.88 | RAB9A (0.66) | NPC1RAB9ASMN1; SMN2HTTPOLB | |
| SCHEMBL1894047 | 0.88 | RAB9A (0.66) | NPC1RAB9ASMN1; SMN2HTTPOLB | |
| SCHEMBL29757933 | 0.87 | SMN1; SMN2 (0.74) | NPC1RAB9ASMN1; SMN2HTTPOLB | |
| SCHEMBL24272365 | 0.87 | SMN1; SMN2 (0.74) | NPC1RAB9ASMN1; SMN2HTTPOLB | |
| SCHEMBL21750906 | 0.84 | RAB9A (0.56) | NPC1RAB9ASMN1; SMN2HTTPOLB | |
| SCHEMBL29757932 | 0.84 | RAB9A (0.56) | NPC1RAB9ASMN1; SMN2HTTPOLB | |
| SCHEMBL18031165 | 0.82 | MAOA (0.67) | NPC1RAB9ASMN1; SMN2HTTPOLB | |
| SCHEMBL3555790 | 0.80 | MET (0.51) | NPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL16946643 | 0.79 | MAPT (0.76) | NPC1RAB9ASMN1; SMN2HTTPOLB | |
| SCHEMBL16621348 | 0.79 | P2RX1 (0.55) | NPC1RAB9ASMN1; SMN2HTTCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023226323-A1 | QUINAZOLINE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 天津济坤医药科技有限公司 | 2023-11-30 | — | — | WO | disclosed |
| EP-1777218-A1 | Process for the preparation of 4-phenoxy quinoline derivatives | Eisai R&D Management Co., Ltd. (JP) | 2007-04-25 | — | — | EP | disclosed |