Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 8/20 | 0.74 |
| ▸ | PDE5A | O76074 | 7/20 | 0.59 |
| ▸ | KIF11 | P52732 | 2/20 | 0.57 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14540797 | 0.87 | PDE5A (0.60) | RIPK1PDE5AKIF11PRKCZ | |
| SCHEMBL18255056 | 0.85 | RIPK1 (1.00) | RIPK1KIF11 | |
| SCHEMBL18248363 | 0.83 | RIPK1 (0.74) | RIPK1KIF11 | |
| SCHEMBL14541223 | 0.82 | PDE5A (0.62) | RIPK1PDE5AALDH1A1MAPT | |
| SCHEMBL14540792 | 0.79 | PDE5A (0.61) | RIPK1PDE5APRKCZ | |
| SCHEMBL25369066 | 0.76 | PDE5A (0.64) | RIPK1PDE5APRKCZ | |
| SCHEMBL12494881 | 0.74 | PDE5A (1.00) | PDE5APRKCZALDH1A1MAPT | |
| SCHEMBL18248356 | 0.74 | RIPK1 (1.00) | RIPK1 | |
| SCHEMBL18248359 | 0.74 | RIPK1 (1.00) | RIPK1 | |
| SCHEMBL18248275 | 0.74 | RIPK1 (1.00) | RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007038425-A2 | ANTI-VIRAL COMPOUINDS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2007-04-05 | — | — | WO | disclosed |