Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 1/20 | 0.60 |
| ▸ | KIF11 | P52732 | 6/20 | 0.58 |
| ▸ | NT5E | P21589 | 1/20 | 0.56 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | EGFR | P00533 | 1/20 | 0.54 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14540791 | 0.87 | RIPK1 (0.74) | PDE5AKIF11RIPK1PRKCZ | |
| SCHEMBL14541148 | 0.86 | PDE5A (0.60) | PDE5AKIF11MAOBNPC1RAB9A | |
| SCHEMBL14541222 | 0.81 | PDE5A (0.64) | PDE5A | |
| SCHEMBL14540792 | 0.80 | PDE5A (0.61) | PDE5ARIPK1MAOBPRKCZ | |
| SCHEMBL9370534 | 0.80 | LMNA (0.75) | KIF11NT5ERIPK1MAOBNPC1 | |
| SCHEMBL1658926 | 0.78 | NT5E (0.82) | KIF11NT5EMAOBNPC1RAB9A | |
| SCHEMBL25369066 | 0.77 | PDE5A (0.64) | PDE5ARIPK1MAOBPRKCZ | |
| SCHEMBL12494881 | 0.75 | PDE5A (1.00) | PDE5APRKCZ | |
| SCHEMBL14541221 | 0.74 | PDE5A (0.64) | PDE5APRKCZ | |
| SCHEMBL28473652 | 0.73 | MAOB (0.79) | KIF11NT5EMAOBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007038425-A2 | ANTI-VIRAL COMPOUINDS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2007-04-05 | — | — | WO | disclosed |