Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 8/20 | 0.43 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 4/20 | 0.41 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.40 |
| ▸ | KIT | P10721 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1894179 | 0.88 | AXL (0.55) | AXLMETPDGFRAPDGFRBKDR | |
| SCHEMBL12663636 | 0.87 | PDGFRA (0.49) | AXLPDGFRAPDGFRBKDRFGFR2 | |
| SCHEMBL1890162 | 0.87 | AXL (0.43) | AXLMETPDGFRAPDGFRBKDR | |
| SCHEMBL14540484 | 0.85 | MET (0.44) | AXLMETPDGFRAPDGFRBKDR | |
| SCHEMBL1895977 | 0.83 | AXL (0.45) | AXLMETPDGFRAPDGFRBKDR | |
| SCHEMBL1893833 | 0.82 | AXL (0.42) | AXLMETPDGFRAPDGFRBKDR | |
| SCHEMBL1890937 | 0.82 | AXL (0.42) | AXLMETPDGFRAPDGFRBKDR | |
| SCHEMBL1893599 | 0.81 | MAOB (0.42) | AXLMETPDGFRAPDGFRBKDR | |
| SCHEMBL14540559 | 0.81 | AXL (0.43) | AXLMETPDGFRAPDGFRBKDR | |
| SCHEMBL12499398 | 0.81 | PDGFRA (0.57) | AXLPDGFRAPDGFRBKDRFGFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1777218-A1 | Process for the preparation of 4-phenoxy quinoline derivatives | Eisai R&D Management Co., Ltd. (JP) | 2007-04-25 | — | — | EP | disclosed |