Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14540741 | 0.81 | FOLH1 (0.41) | PTPN1TTRTHRATHRBPPARG | |
| SCHEMBL3137725 | 0.81 | FOLH1 (0.41) | PTPN1TTRTHRATHRBPPARG | |
| SCHEMBL2166740 | 0.79 | KDM6B (0.53) | PTPN1TTRTHRATHRBPPARG | |
| SCHEMBL2166747 | 0.79 | KDM6B (0.53) | PTPN1TTRTHRATHRBPPARG | |
| SCHEMBL5858308 | 0.78 | PTPN1 (0.44) | PTPN1TTRTHRATHRBPPARG | |
| Dibromotyrosine SCHEMBL145218 | 0.78 | THRB (0.58) | PTPN1TTRTHRATHRBPPARG | |
| Dibromotyrosine SCHEMBL838919 | 0.78 | THRB (0.58) | PTPN1TTRTHRATHRBPPARG | |
| Dibromotyrosine SCHEMBL145219 | 0.78 | THRB (0.58) | PTPN1TTRTHRATHRBPPARG | |
| Dibromotyrosine SCHEMBL29399010 | 0.76 | THRB (0.57) | TTRTHRATHRBPPARGCYP3A4 | |
| SCHEMBL3960051 | 0.75 | CPA1 (0.56) | PTPN1TTRTSHRCYP2C9HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007039125-A2 | AN OPTICALLY ACTIVE THYROID RECEPTOR AGONIST AND OPTICALLY ACTIVE KEY INTERMEDIATES IN ITS PRODUCTION | KARO BIO AB (SE) | 2007-04-12 | — | — | WO | disclosed |