Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14540741 | 0.80 | FOLH1 (0.41) | TRPV1PTPN1THRATHRBPPARG | |
| SCHEMBL3137725 | 0.80 | FOLH1 (0.41) | TRPV1PTPN1THRATHRBPPARG | |
| SCHEMBL2786552 | 0.75 | HSP90AB1 (0.63) | TRPV1HSP90AB1PTPN1THRATHRB | |
| SCHEMBL5077496 | 0.74 | PDK2 (0.41) | TRPV1THRATHRBMEN1KMT2A | |
| SCHEMBL3137118 | 0.73 | FOLH1 (0.44) | TRPV1HSP90AB1PTPN1ESR1MEN1 | |
| SCHEMBL3911299 | 0.73 | FOLH1 (0.41) | TRPV1PTPN1THRATHRBPPARG | |
| SCHEMBL2164006 | 0.73 | FOLH1 (0.41) | TRPV1PTPN1THRATHRBPPARG | |
| SCHEMBL3130670 | 0.72 | TRPV1 (0.44) | TRPV1HSP90AB1PTPN1THRATHRB | |
| SCHEMBL4817111 | 0.72 | FOLH1 (0.40) | TRPV1PTPN1THRATHRBPPARG | |
| SCHEMBL18822126 | 0.72 | THRB (0.47) | TRPV1THRATHRBPPARGESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007039125-A2 | AN OPTICALLY ACTIVE THYROID RECEPTOR AGONIST AND OPTICALLY ACTIVE KEY INTERMEDIATES IN ITS PRODUCTION | KARO BIO AB (SE) | 2007-04-12 | — | — | WO | disclosed |