Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.42 |
| ▸ | RARA | P10276 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5262566 | 0.77 | NPC1 (0.44) | NPC1RAB9AHIF1ARARAPDE4D | |
| SCHEMBL6648245 | 0.74 | ALDH1A1 (0.57) | NPC1RAB9AHIF1APTPN1KDM4E | |
| SCHEMBL5310251 | 0.73 | NPC1 (0.41) | NPC1RAB9AHIF1ARARAHSP90AA1 | |
| SCHEMBL2043165 | 0.72 | NPC1 (0.69) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL24728286 | 0.71 | PDE4D (0.50) | HIF1AHSP90AA1PDE4DPTPN1ALDH1A1 | |
| SCHEMBL30065827 | 0.71 | ALDH1A1 (0.57) | NPC1RAB9AHIF1APTPN1KDM4E | |
| SCHEMBL30435431 | 0.70 | PTPN1 (0.57) | RARAPDE4DPTPN1KDM4EALDH1A1 | |
| SCHEMBL26317244 | 0.69 | NPC1 (0.74) | NPC1RAB9AKDM4ECA12CA9 | |
| SCHEMBL10883360 | 0.68 | NPC1 (0.84) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL7157612 | 0.67 | ACHE (0.61) | HIF1AHSP90AA1PTPN1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007039609-A1 | PYRANODIBENZOFURAN DERIVATIVES WITH ANTIFUNGAL AND ANTIBACTERIAL ACTIVITY | INSTITUT PASTEUR (FR) | 2007-04-12 | — | — | WO | disclosed |