Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24728220 | 0.84 | PDE4D (0.46) | PDE4DPTPN1HIF1AHSP90AA1XDH | |
| SCHEMBL24728697 | 0.83 | RAB9A (0.47) | PDE4DALDH1A1HPGDPTPN1HIF1A | |
| SCHEMBL24728163 | 0.83 | RAB9A (0.52) | PDE4DALDH1A1HPGDPTPN1HIF1A | |
| SCHEMBL29822611 | 0.82 | PDE4D (0.44) | PDE4DALDH1A1PTPN1HIF1AHSP90AA1 | |
| SCHEMBL24728160 | 0.82 | PDE4D (0.44) | PDE4DLMNAALDH1A1PTPN1HIF1A | |
| SCHEMBL24728166 | 0.79 | PTPN1 (0.52) | LMNARECQLALDH1A1CYP3A4HPGD | |
| SCHEMBL24728230 | 0.76 | MAPT (0.45) | LMNAALDH1A1HPGDTDP1PTPN1 | |
| SCHEMBL29822690 | 0.76 | PTPN1 (0.42) | PDE4DALDH1A1PTPN1XDHHIF1AN | |
| SCHEMBL24728304 | 0.76 | PDE4D (0.48) | PDE4DALDH1A1HPGDPTPN1XDH | |
| SCHEMBL24728287 | 0.75 | PTPN1 (0.42) | PDE4DPTPN1HSP90AA1XDHHIF1AN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022158624-A1 | NOVEL BENZOPYRAN DERIVATIVE COMPOUND, PREPARATION METHOD THEREFOR, AND ANTICANCER COMPOSITION COMPRISING SAME | 연세대학교 산학협력단 | 2022-07-28 | — | — | WO | disclosed |