Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 2/20 | 0.59 |
| ▸ | CA1 | P00915 | 4/20 | 0.54 |
| ▸ | CA2 | P00918 | 4/20 | 0.54 |
| ▸ | CA9 | Q16790 | 4/20 | 0.54 |
| ▸ | CA12 | O43570 | 3/20 | 0.54 |
| ▸ | CA4 | P22748 | 1/20 | 0.54 |
| ▸ | TERT | O14746 | 3/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14541223 | 0.89 | PDE5A (0.62) | PDE5AALDH1A1MAPTPKMCA1 | |
| SCHEMBL14541221 | 0.85 | PDE5A (0.64) | PDE5AALDH1A1MAPTPKMLMNA | |
| SCHEMBL14541148 | 0.82 | PDE5A (0.60) | PDE5ACA1CA2CA9CA12 | |
| SCHEMBL14540797 | 0.81 | PDE5A (0.60) | PDE5A | |
| SCHEMBL12494570 | 0.78 | PDE5A (1.00) | PDE5AALDH1A1MAPT | |
| SCHEMBL14541155 | 0.75 | KDM4E (0.79) | PKMCA1CA2CA9CA12 | |
| SCHEMBL15803412 | 0.71 | ALDH1A1 (0.71) | PDE5AALDH1A1MAPT | |
| SCHEMBL25369066 | 0.71 | PDE5A (0.64) | PDE5A | |
| SCHEMBL14133644 | 0.69 | CA1 (0.64) | ALDH1A1PKMCA1CA2CA9 | |
| SCHEMBL6599138 | 0.69 | SLC18A3 (0.47) | ALDH1A1MAPTPKMCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007038425-A2 | ANTI-VIRAL COMPOUINDS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2007-04-05 | — | — | WO | disclosed |