Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | ADH1B | P00325 | 3/20 | 0.31 |
| ▸ | ADH1C | P00326 | 3/20 | 0.31 |
| ▸ | ADH1A | P07327 | 3/20 | 0.31 |
| ▸ | ADH7 | P40394 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ADH4 | P08319 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | SHBG | P04278 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14519177 | 1.00 | ALDH1A1 (0.48) | ALDH1A1HSD17B10ADH1BADH1CADH1A | |
| SCHEMBL14519186 | 1.00 | ALDH1A1 (0.48) | ALDH1A1HSD17B10ADH1BADH1CADH1A | |
| SCHEMBL14519164 | 0.81 | ALDH1A1 (0.52) | ALDH1A1HSD17B10ADH1BADH1CADH1A | |
| SCHEMBL1001868 | 0.81 | ALDH1A1 (0.52) | ALDH1A1HSD17B10ADH1BADH1CADH1A | |
| SCHEMBL2647865 | 0.81 | ALDH1A1 (0.52) | ALDH1A1HSD17B10ADH1BADH1CADH1A | |
| SCHEMBL9736665 | 0.81 | GAA (0.32) | L3MBTL1GAA | |
| SCHEMBL20276191 | 0.79 | CCR2 (0.30) | — | |
| SCHEMBL20276289 | 0.79 | CCR2 (0.30) | — | |
| SCHEMBL25481728 | 0.79 | ADH1B (0.32) | ALDH1A1HSD17B10ADH1BADH1CADH1A | |
| SCHEMBL2647837 | 0.79 | ALDH1A1 (0.57) | ALDH1A1HSD17B10ADH1BADH1CADH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7199147-B2 | Rho kinase inhibitors | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2007-04-03 | — | — | US | disclosed |