Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24283915 | 0.92 | PKM (0.40) | PKMALDH1A1NPSR1CA9CA12 | |
| SCHEMBL23892773 | 0.86 | ALDH1A1 (0.43) | PKMALDH1A1NPSR1CA9CA12 | |
| SCHEMBL22571484 | 0.85 | MGLL (0.36) | PKMALDH1A1NPSR1CA9CA12 | |
| SCHEMBL25751339 | 0.84 | NPSR1 (0.40) | PKMALDH1A1NPSR1CA9CA12 | |
| SCHEMBL25865571 | 0.83 | ALDH1A1 (0.41) | PKMALDH1A1NPSR1CA9CA12 | |
| SCHEMBL18823084 | 0.82 | CA9 (0.48) | PKMALDH1A1NPSR1CA9CA12 | |
| SCHEMBL13821869 | 0.82 | CA9 (0.37) | ALDH1A1NPSR1CA9CA12CA1 | |
| SCHEMBL13951560 | 0.82 | NPSR1 (0.38) | PKMALDH1A1NPSR1CA9CA12 | |
| SCHEMBL24417878 | 0.81 | NPC1 (0.39) | ALDH1A1CA9CA12CA1CA2 | |
| SCHEMBL21168257 | 0.81 | PKM (0.44) | PKMALDH1A1NPSR1CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7208109-B2 | Changing the solution to nonflowable by absorbing a coagulant, then solvent extraction, for molding a solution of a liquid crystal polymer, polybenzoxazoles or polybenzothiazoles | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 2007-04-24 | — | — | US | disclosed |