Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.32 |
| ▸ | MPL | P40238 | 1/20 | 0.31 |
| ▸ | SLC7A11 | Q9UPY5 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14546783 | 1.00 | THRB (0.33) | THRBENPP2SMN1; SMN2PHLPP2MPL | |
| SCHEMBL14546785 | 1.00 | THRB (0.33) | THRBENPP2SMN1; SMN2PHLPP2MPL | |
| SCHEMBL14546918 | 0.94 | THRB (0.36) | THRBENPP2PHLPP2ALDH1A1KDM4E | |
| SCHEMBL14546755 | 0.92 | ENPP2 (0.38) | THRBENPP2PHLPP2MPLSLC7A11 | |
| SCHEMBL14546740 | 0.92 | ENPP2 (0.38) | THRBENPP2PHLPP2MPLSLC7A11 | |
| SCHEMBL12053068 | 0.92 | — | — | |
| SCHEMBL12053076 | 0.92 | — | — | |
| SCHEMBL14546965 | 0.90 | THRB (0.43) | THRBENPP2PHLPP2SLC7A11ALDH1A1 | |
| SCHEMBL14546985 | 0.90 | THRB (0.43) | THRBENPP2PHLPP2SLC7A11ALDH1A1 | |
| SCHEMBL14546966 | 0.90 | THRB (0.43) | THRBENPP2PHLPP2SLC7A11ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007039573-A2 | AZO REACTIVE DYES AND MIXTURES OF FIBER-REACTIVE AZO DYES, THEIR PREPARATION AND THEIR USE | DYSTAR TEXTILFARBEN GMBH & CO DEUTSCHLAND KG (DE) | 2007-04-12 | — | — | WO | disclosed |