Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.33 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | NMT2 | O60551 | 1/20 | 0.32 |
| ▸ | NMT1 | P30419 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12334999 | 0.87 | ALDH1A1 (0.55) | ALDH1A1LMNAPKMCNR1HPGD | |
| SCHEMBL8239576 | 0.85 | DNM1 (0.37) | ALDH1A1LMNADNM1HPGDKDM4A | |
| Poly(Amidoamine)Dendrimer SCHEMBL13964588 | 0.85 | DNM1 (0.37) | ALDH1A1LMNADNM1HPGDKDM4A | |
| SCHEMBL21202619 | 0.83 | TP53 (0.35) | ALDH1A1LMNADNM1TP53HTT | |
| SCHEMBL8739595 | 0.83 | ALDH1A1 (0.39) | ALDH1A1LMNAPKMDNM1CNR1 | |
| SCHEMBL12219612 | 0.83 | KDM4A (0.38) | ALDH1A1LMNADNM1HPGDKDM4A | |
| SCHEMBL10081612 | 0.82 | CASP2 (0.46) | ALDH1A1DNM1HPGDKDM4AHIF1A | |
| SCHEMBL12946149 | 0.82 | DNM1 (0.40) | ALDH1A1LMNADNM1KDM4AHIF1A | |
| SCHEMBL15293155 | 0.82 | PAOX (0.43) | ALDH1A1LMNADNM1KDM4AHIF1A | |
| SCHEMBL13254848 | 0.82 | CASP2 (0.46) | ALDH1A1DNM1HPGDKDM4AHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2543659-A1 | DENDRIMERS AS NON-VIRAL VEHICLES FOR GENE THERAPY | Universidad De Castilla La Mancha (ES) | 2013-01-09 | — | — | EP | disclosed |