Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.42 |
| ▸ | HPGD | P15428 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 4/20 | 0.42 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diethylamine SCHEMBL2361776 | 0.84 | NPSR1 (0.53) | KDM4EHPGDALDH1A1HSD17B10HTT | |
| SCHEMBL12651524 | 0.78 | KDM4E (0.44) | SRCKDM4EHPGDALDH1A1TSHR | |
| SCHEMBL2360961 | 0.77 | CNR2 (0.42) | SRCKDM4EHPGDALDH1A1TSHR | |
| SCHEMBL12608636 | 0.76 | ALDH1A1 (0.35) | SRCKDM4EHPGDALDH1A1GPR35 | |
| SCHEMBL12608638 | 0.76 | ALOX15 (0.35) | SRCKDM4EHPGDALDH1A1HTT | |
| SCHEMBL28922531 | 0.73 | NPSR1 (0.56) | KDM4EHPGDALDH1A1HSD17B10HTT | |
| SCHEMBL2361775 | 0.73 | HIF1A (0.52) | KDM4EHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL12608683 | 0.72 | CNR2 (0.44) | KDM4EHPGDALDH1A1HTTMEN1 | |
| SCHEMBL12608693 | 0.72 | CNR2 (0.39) | SRCKDM4EALDH1A1TSHRHTT | |
| SCHEMBL17297962 | 0.72 | CNR2 (0.41) | SRCKDM4EALDH1A1TSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2356093-B1 | Carbazole compounds and therapeutic uses of the compounds | INCURON LLC (RU) | 2013-01-09 | — | — | EP | disclosed |