Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25626868 | 0.70 | ALOX5 (0.37) | ALOX5EPHX1 | |
| SCHEMBL31122647 | 0.68 | ALOX5 (0.42) | ALOX5NOS1NOS2EPHX1 | |
| SCHEMBL11903803 | 0.67 | CYP1A2 (0.37) | ALOX5NOS1NOS2 | |
| SCHEMBL10486372 | 0.67 | EPHX1 (0.48) | ALOX5NOS1NOS2EPHX1 | |
| SCHEMBL17917632 | 0.66 | — | — | |
| SCHEMBL11662768 | 0.65 | EPHX1 (0.52) | ALOX5EPHX1 | |
| SCHEMBL11659426 | 0.65 | EPHX1 (0.52) | ALOX5EPHX1 | |
| SCHEMBL5604360 | 0.65 | CYP1A2 (0.43) | ALOX5EPHX1 | |
| SCHEMBL12166781 | 0.65 | CA1 (0.41) | ALOX5 | |
| SCHEMBL28083608 | 0.65 | OPRM1 (0.45) | ALOX5EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1921078-B1 | MULTIKINASE INHIBITOR | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2013-01-09 | — | — | EP | disclosed |