Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.64 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.54 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | KIF11 | P52732 | 1/20 | 0.50 |
| ▸ | CDK8 | P49336 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 3/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | XDH | P47989 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30201504 | 1.00 | ALDH1A1 (0.64) | ALDH1A1KDM4EHSD17B10HPGDENPP2 | |
| Hydrochloric Acid SCHEMBL28263913 | 0.98 | ALDH1A1 (0.62) | ALDH1A1KDM4EHSD17B10HPGDENPP2 | |
| Acetic Acid SCHEMBL28248344 | 0.95 | ALDH1A1 (0.63) | ALDH1A1KDM4EHSD17B10HPGDENPP2 | |
| SCHEMBL28247653 | 0.94 | KDM4E (0.57) | ALDH1A1KDM4EHSD17B10HPGDENPP2 | |
| SCHEMBL29983717 | 0.90 | ALDH1A1 (0.53) | ALDH1A1KDM4EHSD17B10HPGDENPP2 | |
| SCHEMBL29377304 | 0.86 | TUBB4A (0.58) | TAS1R3TAS1R1CDK8NPC1MAPT | |
| SCHEMBL103794 | 0.86 | TUBB4A (0.58) | TAS1R3TAS1R1CDK8NPC1MAPT | |
| SCHEMBL28109570 | 0.85 | KDM4E (0.55) | ALDH1A1KDM4EHSD17B10HPGDENPP2 | |
| Ammonia Solution, Strong SCHEMBL28339305 | 0.85 | TUBB4A (0.57) | TAS1R3TAS1R1CDK8NPC1MAPT | |
| Hydrochloric Acid SCHEMBL28263909 | 0.85 | TUBB4A (0.57) | TAS1R3TAS1R1CDK8NPC1LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1198 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115894329-B | Synthesis method of indole derivative containing 2-thiocyano-3-aryl by axial chirality | 泽升科技(广州)有限公司 | 2023-08-18 | — | — | CN | claimed |
| CN-114354942-A | Microfluidic chip, kit and method for detecting beta-amyloid 1-42 | 江苏汇先医药技术有限公司 | 2022-04-15 | — | — | CN | claimed |
| CN-110117246-A | A kind of preparation method of 3- indoles pimelie kelone compounds | 山西大学 | 2019-08-13 | — | — | CN | claimed |
| CN-107922389-A | 3 amino, 1,5,6,7 tetrahydrochysene 4H indoles, 4 ketone | 拜耳制药股份公司 | 2018-04-17 | — | — | CN | claimed |
| CN-106008306-A | Substituted indole derivatives, and preparation method and application thereof | 山东大学 | 2016-10-12 | — | — | CN | claimed |
| EP-1893588-A1 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | Boehringer Ingelheim International GmbH (DE) | 2008-03-05 | — | — | EP | claimed |
| CN-100345850-C | 3-phenyl-substituted pyridoindolones, their preparation and therapeutic use | SANOFI AVENTIS (FR) | 2007-10-31 | — | — | CN | claimed |
| WO-2006135826-A1 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-12-21 | — | — | WO | claimed |
| CN-1729190-A | 3-phenyl-substituted pyridoindolones, their preparation and therapeutic use | SANOFI AVENTIS (FR) | 2006-02-01 | — | — | CN | claimed |
| CN-1633296-A | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof | BOEHRINGER INGELHEIM PHARMA (US) | 2005-06-29 | — | — | CN | claimed |
| CN-1024626-C | Tetrahydrobenz [c,d] indole serotonin agonists | LILLY CO ELI (US) | 1994-05-25 | — | — | CN | claimed |
| CN-1046330-A | Tetrahydro benzo [c, d] indole serotonin stimulant | LILLY CO ELI (US) | 1990-10-24 | — | — | CN | claimed |
| JP-7053558-A | — | — | None | — | — | JP | disclosed |
| EP-4744661-A2 | NOVEL PYRIMIDIN-2-YL SULFONAMIDE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2026-05-20 | — | — | EP | disclosed |
| US-12606557-B2 | Substituted indoles with inhibitory activity | UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2026-04-21 | — | — | US | disclosed |
| US-12559455-B2 | Compound as a UBR box domain ligand | AUTOTAC INC. (KR) | 2026-02-24 | — | — | US | disclosed |
| EP-0179619-A1 | Heterocyclic amides | ICI AMERICAS INC. (US) | 1986-04-30 | — | — | EP | disclosed |
| US-4493843-A | Indole and indoline carboxylic acid compounds and method of use | MAY & BAKER LIMITED (GB) | 1985-01-15 | — | — | US | disclosed |
| EP-0042298-B1 | INDOLE AND INDOLINE DERIVATIVES | MAY & BAKER LIMITED (GB) | 1984-09-12 | — | — | EP | disclosed |
| EP-0042298-A1 | Indole and indoline derivatives | MAY & BAKER LIMITED (GB) | 1981-12-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12606557-B2 | Substituted indoles with inhibitory activity | IDO1, BCL9, IDO2 | ALDH1A1 754/4885KDM4E 1848/4885HSD17B10 570/4885 |
| US-12559455-B2 | Compound as a UBR box domain ligand | UBR4, UBTF, UBQLN1 | ALDH1A1 1486/4885KDM4E 707/4885HSD17B10 1707/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.