SCHEMBL103794

SCHEMBL103794

COC(=O)c1ccc2[nH]ccc2c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TUBB4A P04350 1/20 0.58
TUBB P07437 1/20 0.58
TUBA3C P0DPH7 1/20 0.58
TUBA1B P68363 1/20 0.58
TUBA4A P68366 1/20 0.58
TUBB4B P68371 1/20 0.58
TUBB3 Q13509 1/20 0.58
TUBB2A Q13885 1/20 0.58
TUBB8 Q3ZCM7 1/20 0.58
TUBA3E Q6PEY2 1/20 0.58
TUBA1A Q71U36 1/20 0.58
TUBA1C Q9BQE3 1/20 0.58
TUBB6 Q9BUF5 1/20 0.58
TUBB2B Q9BVA1 1/20 0.58
TUBB1 Q9H4B7 1/20 0.58
TAS1R3 Q7RTX0 1/20 0.54
TAS1R1 Q7RTX1 1/20 0.54
RAB9A P51151 2/20 0.54
CYP1A2 P05177 1/20 0.54
CYP3A4 P08684 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29377304 1.00 TUBB4A (0.58) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
Hydrochloric Acid SCHEMBL28263909 0.98 TUBB4A (0.57) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
Ammonia Solution, Strong SCHEMBL28339305 0.98 TUBB4A (0.57) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
Acetic Acid SCHEMBL7849384 0.95 TUBB4A (0.55) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
Formic Acid SCHEMBL28633278 0.94 TUBB4A (0.53) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
Pyridine SCHEMBL28511930 0.89 CTNNB1 (0.50) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL30201504 0.86 ALDH1A1 (0.64) TAS1R3TAS1R1MAPTNPC1CDK8
SCHEMBL145507 0.86 ALDH1A1 (0.64) TAS1R3TAS1R1MAPTNPC1CDK8
Hydrochloric Acid SCHEMBL28263913 0.85 ALDH1A1 (0.62) TAS1R3TAS1R1MAPTNPC1CDK8
SCHEMBL18941059 0.84 ABL1 (0.49) TUBB4ATUBBTUBA3CTUBA1BTUBA4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1126 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118437307-A Application of amorphous carbon material and synthetic method of poly-deuterated aromatic compound 无锡绿能电合科技有限公司 2024-08-06 CN claimed
CN-106831793-B A kind of synthesis technology for treating ovarian cancer Rucaparib intermediate 青岛大学附属医院 2019-01-22 CN claimed
CN-106831793-A A kind of synthesis technique for treating ovarian cancer Rucaparib intermediates 青岛辰达生物科技有限公司 2017-06-13 CN claimed
EP-3080099-A1 INHIBITORS OF BRUTON'S TYROSINE KINASE F. Hoffmann-La Roche AG (CH) 2016-10-19 EP claimed
WO-2015086642-A1 INHIBITORS OF BRUTON'S TYROSINE KINASE F. HOFFMANN-LA ROCHE AG (CH) 2015-06-18 WO claimed
CN-101374842-A Azepinoindole derivatives as pharmaceutical agents EXELIXIS INC (US) 2009-02-25 CN claimed
US-12577243-B2 Monoacylglycerol lipase modulators JANSSEN PHARMACEUTICA NV (BE) 2026-03-17 US disclosed
EP-3856178-B1 MONOACYLGLYCEROL LIPASE MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2026-03-11 EP disclosed
US-12534474-B2 Dihydrofuropyridine derivatives as rho-kinase inhibitors CHIESI FARMACEUTICI S.P.A. (IT) 2026-01-27 US disclosed
US-12485109-B2 Pyrrolo 12.3-dipyrimidine compounds and analogues thereof BIOCRYST PHARMACEUTICALS, INC. (US) 2025-12-02 US disclosed
US-12428411-B2 Preparation of oxindole derivatives as novel diacylglyceride o-acyltransferase 2 inhibitors MERCK SHARP & DOHME LLC (US) 2025-09-30 US disclosed
US-12410159-B2 Preparation of oxindole derivatives as novel diacylglyceride O-acyltransferase 2 inhibitors MERCK SHARP & DOHME LLC (US) 2025-09-09 US disclosed
EP-4584263-A1 1,3,4-OXADIAZOLE DERIVATIVE COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND USES THEREOF Chong Kun Dang Pharmaceutical Corp. (KR) 2025-07-16 EP disclosed
CN-1030910-A ALIPHATIC CARBOXAMIDEX ICI AMERICA INC (US) 1989-02-08 CN disclosed
US-4795756-A VASOCONSTRICTOR FOR MIGRAINE HEADACHE GLAXO GROUP LIMITED (GB) 1989-01-03 US disclosed
EP-0290145-A1 Aliphatic carboxamides ZENECA INC. (US) 1988-11-09 EP disclosed
US-4734407-A ANIMAL GROWTH REGULATORS BAYER AKTIENGESELLSCHAFT (DE) 1988-03-29 US disclosed
US-4493843-A Indole and indoline carboxylic acid compounds and method of use MAY & BAKER LIMITED (GB) 1985-01-15 US disclosed
EP-0042298-B1 INDOLE AND INDOLINE DERIVATIVES MAY & BAKER LIMITED (GB) 1984-09-12 EP disclosed
EP-0042298-A1 Indole and indoline derivatives MAY & BAKER LIMITED (GB) 1981-12-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12485109-B2 Pyrrolo 12.3-dipyrimidine compounds and analogues thereof C5, DPYD, C9 TUBB4A 4502/4885TUBB 4424/4885TUBA3C 4030/4885
US-12577243-B2 Monoacylglycerol lipase modulators MGLL, LPL, FAAH TUBB4A 3091/4885TUBB 2419/4885TUBA3C 2397/4885
US-12534474-B2 Dihydrofuropyridine derivatives as rho-kinase inhibitors ROCK1, RHOC, ROCK2 TUBB4A 1023/4885TUBB 910/4885TUBA3C 484/4885
US-12410159-B2 Preparation of oxindole derivatives as novel diacylglyceride O-acyltransferase 2 inhibitors DGAT2, DGAT1, MOGAT2 TUBB4A 4467/4885TUBB 4319/4885TUBA3C 4598/4885
US-12428411-B2 Preparation of oxindole derivatives as novel diacylglyceride o-acyltransferase 2 inhibitors DGAT2, DGAT1, MOGAT2 TUBB4A 4467/4885TUBB 4319/4885TUBA3C 4598/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.