SCHEMBL14552127

SCHEMBL14552127

CC(=O)N[C@@H](CCS)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CS)C(=O)N[C@H](C)CO

nearest known ligand 0.54

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ MC4R P32245 5/20 0.54
▸ KISS1R Q969F8 4/20 0.54
▸ IL23R Q5VWK5 11/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30014698 0.90 MC4R (0.56) MC4RKISS1RIL23R
SCHEMBL28940921 0.90 MC4R (0.56) MC4RKISS1RIL23R
SCHEMBL29420167 0.90 MC4R (0.64) MC4RKISS1R
SCHEMBL12057583 0.90 MC4R (0.64) MC4RKISS1R
SCHEMBL14552580 0.88 MC4R (0.54) MC4RKISS1RIL23R
SCHEMBL14552192 0.88 CTSL (0.52) MC4RKISS1RIL23R
SCHEMBL14552701 0.88 MC4R (0.54) MC4RKISS1RIL23R
SCHEMBL14552557 0.87 CTSL (0.55) MC4RKISS1RIL23R
SCHEMBL30264726 0.87 GHSR (0.53) MC4RKISS1R
SCHEMBL29476431 0.87 GHSR (0.53) MC4RKISS1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130012432-A1 Peptides for Treatment of Obesity NOVO NORDISK A/S (DK) 2013-01-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130012432-A1 Peptides for Treatment of Obesity MC4R, GIPR, MC3R MC4R 1/4885KISS1R 139/4885IL23R 698/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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